ulcer patients with omeprazole and amoxicillin
نویسندگان
چکیده
Accepted for publication 10 November 1994 Abstract Omeprazole plus amoxicillin cures Helicobacter pyloni infection. The hypothesis was tested that low acidity is a predictor of outcome. Fifty patients with relapsing or complicated, or both Hpylori positive duodenal (n=25) or gastric ulcer (n=25) were randomly treated with either omeprazole 20 mg twice daily plus amoxicillin 1 g twice daily or with omeprazole 40 mg twice daily plus amoxicillin 1 g twice daily over two weeks. After one week of combined treatment, a 24 hour gastric pH measurement was performed in all patients. H pylon cure rate was 67%. Patients who later turned out to be cured had higher pH values during night time and after meals (p<0.05). In an explorative analysis drug compliance, smoking, location of the ulcer (duodenum
منابع مشابه
Intragastric acidity as a predictor of the success of Helicobacter pylori eradication: a study in peptic ulcer patients with omeprazole and amoxicillin.
Omeprazole plus amoxicillin cures Helicobacter pylori infection. The hypothesis was tested that low acidity is a predictor of outcome. Fifty patients with relapsing or complicated, or both H pylori positive duodenal (n = 25) or gastric ulcer (n = 25) were randomly treated with either omeprazole 20 mg twice daily plus amoxicillin 1 g twice daily or with omeprazole 40 mg twice daily plus amoxicil...
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